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KMID : 0361120160300010044
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Korean Journal of Transplantation
2016 Volume.30 No. 1 p.44 ~ p.49
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Post-transplant Lymphoproliferative Disorder in Transplanted Kidney Causing Urinary Tract Obstruction
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Park Hyeon-Cheol
Kim Jae-Seok
Kong Jee-Hyun
Kim Sung-Hoon
Park Sang-Wook
Song Shin-Han
Yang Jae-Won
Han Byoung-Geun
Choi Seung-Ok
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Abstract
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Post-transplant lymphoproliferative disorder (PTLD) is a serious complication resulting in mortality and renal graft failure. PTLD is a heterogeneous disorder, which causes different clinical forms of disease from non-specific viral syndrome to malignant lymphoma and has various etiologies, clinical features, and treatment strategies. Here, we report on a patient who had a PTLD in the hilum of a transplanted kidney at 5 months after renal transplantation. The PTLD resulted in hydronephrosis of the transplanted kidney and graft dysfunction by local urinary tract obstruction. Despite treatment including immunosuppression reduction and rituximab administration, we removed the transplanted kidney from the recipient because the PTLD did not respond to the therapy.
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KEYWORD
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Lymphoproliferative disorders, Kidney transplantation, Hydronephrosis
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